Clinical Trial: Methotrexate and Cytosine in Adult Langerhans Cell Histiocytosis

Study Status: Recruiting
Recruit Status: Recruiting
Study Type: This single arm clinical trial is studying efficacy and tolerance of combination chemotherapy with m

Official Title: Efficacy and Tolerance of Combination Chemotherapy With Methotrexate and Cytosine Arabinoside in Newly Diagnosed Adult With Langerhans Cell Histiocytosis

Brief Summary:

Study Type: Interventional

Study Design:

Endpoint Classification: Efficacy Study Intervention Model: Single Group Assignment Masking: Open Label Primary Purpose: Treatment purpose: This single arm clinical trial is studying efficacy and tolerance of combination chemotherapy with methotrexate and cytosine arabinoside in newly diagnosed adult with Langerhans cell histiocytosis.

Detailed Summary: This single arm clinical trial is studying efficacy and tolerance of combination chemotherapy with methotrexate and cytosine arabinoside in newly diagnosed adult with Langerhans cell histiocytosis.
Sponsor: Peking Union Medical College Hospital

Current Primary Outcome: disease free survival [ Time Frame: 5 years ]

Original Primary Outcome: Same as current

Current Secondary Outcome: overall free survival [ Time Frame: 5 years ]

Original Secondary Outcome: Same as current

Information By: Peking Union Medical College Hospital

Dates:
Date Received: February 9, 2015
Date Started: January 2014
Date Completion: December 2020
Last Updated: March 10, 2015
Last Verified: March 2015