Clinical Trial: Role of B2 Adrenergic Receptors in Labor Pain

Study Status: Completed
Recruit Status: Completed
Study Type: Observational

Official Title: Role of B2 Adrenergic Receptors in Labor Pain

Brief Summary: We wish to understand why labor is more painful for some women compared to others.We will study whether a woman's baseline pain sensitivity, beta2 adrenergic receptor genotype is related to her pain in labor for the birth of a first child.

Detailed Summary: Other than parity, and infant size, the etiology of the great variability in labor pain us unknown. Previous studies have demonstrated that baseline pain sensitivity is related to postoperative pain and narcotic requirement. We hypothesize that baseline pain sensitivity is related to pain in labor. We will determine baseline sensitivity to heat, cold and pressure as measurement of pain sensitivity. Furthermore, b2 adrenergic genotype has recently been identified as a potential determinant of pain sensitivity. We will determine whether B2 receptor haplotype is an independent predictor of pain experienced in labor.
Sponsor: Columbia University

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Information By: Columbia University

Dates:
Date Received: October 5, 2006
Date Started: September 2006
Date Completion:
Last Updated: October 1, 2010
Last Verified: October 2010