Clinical Trial: Effect of Goserelin (Zoladex®) in Spinal and Bulbar Muscular Atrophy
Study Status: Completed
Recruit Status: Completed
Study Type: Interventional
Official Title: Effect of Goserelin (Zoladex®) in Spinal and Bulbar Muscular Atrophy in Thai Patients
Brief Summary:
This is a therapeutic trial study to demonstrate whether Goserelin, a LHRH agonist has benefit in SBMA
Objective:
- To study effects of Goserelin to clinical course of patients with spinal and bulbar muscular atrophy in Thailand
- To demonstrate physiological and pathological changes in treated patients with Goserelin.
- To assess tolerability and adverse effect of Goserelin therapy
Detailed Summary:
Sponsor: Ramathibodi Hospital
Current Primary Outcome: muscle power [ Time Frame: every 3 months ]
Original Primary Outcome: Same as current
Current Secondary Outcome: electrophysiologic study (Nerve conduction and Electromyogram) [ Time Frame: every 3 months ]
Original Secondary Outcome: Same as current
Information By: Ramathibodi Hospital
Dates:
Date Received: February 25, 2009
Date Started: April 2008
Date Completion:
Last Updated: May 20, 2015
Last Verified: February 2009
