Clinical Trial: Human Menopausal Gonadotropin Combining With Human Chorionic Gonadotropin Treat Congenital Hypogonadotropic Hypogonadism

Study Status: Recruiting
Recruit Status: Recruiting
Study Type: Interventional

Official Title: Human Menopausal Gonadotropin Combining With Human Chorionic Gonadotropin is Superior to Human Chorionic Gonadotropin in Therapeutic Efficacy in Adolescent Boys With Congenital Hypogonadotropic Hypogo

Brief Summary: Observe the therapeutic efficacy of human menopausal gonadotropin combining with human chorionic gonadotropin in adolescent boys with congenital hypogonadotropic hypogonadism.

Detailed Summary: Observe safety and efficacy of human menopausal gonadotropin and human chorionic gonadotropin treating congenital hypogonadotropic hypogonadism in teenagers; which as clinic recommendation, may provide clinical basis for establishing standard treatment guideline in the future. Establish technological process and follow-up precept for human menopausal gonadotropin and human chorionic gonadotropin injection treating congenital hypogonadotropic hypogonadism in teenagers. And find safety and effective dose for teenagers.
Sponsor: Beijing Children's Hospital

Current Primary Outcome: testicular volume [ Time Frame: Change from Baseline testicular volume at 3 months after treatment ]

Original Primary Outcome: Same as current

Current Secondary Outcome: The levels of testosterone serum (It were measured with chemiluminescent immunoassay Elecsys) [ Time Frame: Testosterone changes from 3 months onwards after treatment compared to pretreatment ]

Original Secondary Outcome: Same as current

Information By: Beijing Children's Hospital

Dates:
Date Received: August 11, 2016
Date Started: August 2016
Date Completion: December 2018
Last Updated: August 25, 2016
Last Verified: August 2016