Clinical Trial: Ridge Preservation Comparing the Healing With or Without a Barrier Membrane
Study Status: Not yet recruiting
Recruit Status: Not yet recruiting
Study Type: Interventional
Official Title: Ridge Preservation Comparing the Clinical and Histologic Healing of Membrane vs. no Membrane Approach to Grafting.
Brief Summary: Ridge Preservation Comparing the Clinical and Histologic Healing of Membrane vs. no Membrane Approach to Grafting.
Detailed Summary: Thirty patients will be treated using the principles of bone grafting for ridge preservation. Fifteen test patients will receive a flap technique with an intrasocket cancellous cortical particulate allograft plus a facial overlay graft using a bovine xenograft without a membrane where only the exposed intrasocket allograft will be covered with a piece of Alloderm GBR. The positive control group of fifteen patients will receive a flap technique with an intrasocket cancellous cortical particulate allograft plus a facial overlay graft using a bovine xenograft plus Alloderm GBR membrane. Approximately, four months post-surgery, a trephine core will be taken from the grafted site immediately prior to implant placement and submitted for histologic processing.
Sponsor: University of Louisville
Current Primary Outcome: Change in post-extraction site to 4 month change in crestal osseous width [ Time Frame: 4 months ]
Original Primary Outcome: Same as current
Current Secondary Outcome:
- Change in Soft tissue thickness [ Time Frame: 4 months ]Soft tissue thickness measurements taken with a #40 endodontic reamer.
- Percent osseous tissue [ Time Frame: 4 months ]A trephine core will be harvested at 4 months. Following histologic processing the osseous core will be classified into percent vital bone, nonvital bone and trabecular space.
Original Secondary Outcome: Same as current
Information By: University of Louisville
Dates:
Date Received: June 9, 2016
Date Started: July 2016
Date Completion: June 2017
Last Updated: June 9, 2016
Last Verified: June 2016