Clinical Trial: Patient Attributes for Optimal Treatment Outcome in Irritable Bowel Syndrome.
Study Status: Completed
Recruit Status: Unknown status
Study Type: Interventional
Official Title: Examining Patient Attributes To Determine Optimal Treatment Outcome in Irritable Bowel Syndrome.
Brief Summary: The purpose of this study is to determine if any specific patient characteristics lead to improved outcome of IBS treatment, when conventional treatment as well as Cognitive Behavioral Therapy is used in combination.
Detailed Summary: Although research has demonstrated the efficacy of various psychological and pharmacological treatments for irritable bowel syndrome (IBS)1, health professionals have limited information about how to determine which specific treatment regimens lead to optimal outcomes for specific IBS populations 2,3. A prevalent syndrome, with high healthcare costs, IBS is a debilitating chronic functional bowel disorder with increasingly interconnected psychosocial and gastrointestinal afflictions4. In general, IBS sufferers have not been found to respond consistently to a single medication or class of medications5. In the wake of the failures of medical therapies, many psychological interventions, adjunct to standard IBS treatments, have been examined1,6 such as Blanchard and Scharff's 2002 review of 12 random controlled trials that found strong evidence for the utility of hypnotherapy, cognitive behavioral therapy (CBT), and brief psychodynamic psychotherapy in helping to alleviate IBS symptoms7. Similarly, in a more recent study involving a meta-analysis of seventeen studies, with randomized trials comparing classes of psychological interventions, found that these psychological treatments also play a role in improving quality of life of IBS suffers1. Among these psychological interventions, cognitive behavioral therapy (CBT), a prescriptive therapy that specifically targets faulty thinking patterns, has been found to be quite effective in many empirical investigations. Recent evaluations of CBT interventions have found the therapy to have a direct effect on global improvements of IBS symptoms and quality of life8. Despite its demonstrated effectiveness, however, CBT does not work for all patients3,6,8. The successes of medical therapy alone compared to a treatment regimen combining psychological and pharmaceutical interventions have been greeted with mixed results— leading to the unnecessary waste of health resources in the course of treatment3,6. To decrease medical cost
Sponsor: Michigan Gastroenterology Institute
Current Primary Outcome: IBS Quality of Life Inventory(IBS QOLF) [ Time Frame: 6 months ]
Original Primary Outcome: IBS Quality of Life Inventory [ Time Frame: 6 months ]
Current Secondary Outcome: Behavioral Symptom Inventory [ Time Frame: 6 months ]
Original Secondary Outcome: Same as current
Information By: Michigan Gastroenterology Institute
Dates:
Date Received: February 15, 2011
Date Started: April 2011
Date Completion: December 2011
Last Updated: February 15, 2011
Last Verified: February 2011
