Clinical Trial: Hypofractionated Stereotactic Linear Accelerator Radiotherapy of Uveal Melanoma

Study Status: Recruiting
Recruit Status: Recruiting
Study Type: Interventional

Official Title: Safety and Efficacy of Hypofractionated Stereotactic Linear Accelerator Radiotherapy of Malignant Melanoma of the Uvea

Brief Summary: The purpose of this study is to assess the safety and efficacy of hypofractionated stereotactic LINAC radiotherapy with 10 fractions at 6 Gy per fraction at the 80% isodose for the planning target volume (PTV) in patients with uveal melanoma. Patients will be followed-up for 10 years after radiotherapy regarding local tumor control, visual acuity, secondary complications and survival.

Detailed Summary:
Sponsor: Medical University of Vienna

Current Primary Outcome: local tumor control (tumor dimensions; secondary complications; visual acuity; survival

Original Primary Outcome: Same as current

Current Secondary Outcome: histological assessment of the fraction of living cells in eyes requiring secondary enucleation

Original Secondary Outcome: Same as current

Information By: Medical University of Vienna

Dates:
Date Received: March 30, 2009
Date Started: March 2009
Date Completion:
Last Updated: March 30, 2009
Last Verified: March 2009