Clinical Trial: Serum Autotaxin Levels in Cholestasis of Pregnancy

Study Status: Recruiting
Recruit Status: Recruiting
Study Type: Observational

Official Title: Diagnostic Accuracy of Serum Autotaxin Levels in Cholestasis of Pregnancy

Brief Summary: Intrahepatic cholestasis of pregnancy is the most common liver disease in pregnancy. It is is a pregnancy-specific liver disorder with onset mainly in the third trimester of pregnancy. ICP is characterized by pruritus, elevated serum fasting bile salts and transaminases and an increased risk of adverse fetal outcomes. Serum autotaxin levels were found highly sensitive and specific biomarker to to differentiate ICP from other pregnancy-related liver disorders or pruritic dermatoses. The purpose of the study is to determine the diagnostic accuracy of serum autotaxin activity in cholestasis of pregnancy.

Detailed Summary: Collected data will enable us to compare serum autotaxin levels in cholestasis of pregnancy and healthy control group.
Sponsor: Sisli Etfal Training & Research Hospital

Current Primary Outcome: Serum autotaxin levels in cholestasis of pregnancy [ Time Frame: one year ]

Original Primary Outcome: Same as current

Current Secondary Outcome:

Original Secondary Outcome:

Information By: Sisli Etfal Training & Research Hospital

Dates:
Date Received: June 21, 2015
Date Started: June 2015
Date Completion: January 2017
Last Updated: April 19, 2016
Last Verified: April 2016