Clinical Trial: A Continuous, Non-Invasive, Real-time Method for Estimating and Predicting Intracranial Hypertension
Study Status: Active, not recruiting
Recruit Status: Active, not recruiting
Study Type: Observational
Official Title: A Continuous, Non-Invasive, Real-time Method for Estimating and Predicting Intracranial Hypertension
Brief Summary:
There is statistically significant correlation between invasive measures of intracranial pressure (ICP) and non-invasive, real-time, continuous physiologic waveform data algorithms to predict ICP. Furthermore, characteristics within this physiologic waveform data will allow modeling for trend prediction of derived ICP information. Specific aims:
- Develop models to estimate ICP and cerebral perfusion pressure (CPP) after traumatic brain injury in humans.
- Predict and anticipate changes in ICP for preemptive management purposes.
- Analyze characteristics of changes in ICP after treatment failure.
- Analyze data to predict/anticipate confounding physiologic factors that affect ICP and its treatment.
- Test the resulting models in real time.
Detailed Summary:
Sponsor: University of Colorado, Denver
Current Primary Outcome: Algorithm development [ Time Frame: 24 months ]
Original Primary Outcome:
Current Secondary Outcome:
Original Secondary Outcome:
Information By: University of Colorado, Denver
Dates:
Date Received: October 5, 2011
Date Started: August 2011
Date Completion: November 2017
Last Updated: December 1, 2016
Last Verified: December 2016