Clinical Trial: The Study of Using Esophageal Pressure to Guide the PEEP Setting in Abdominal Hypertension Patients Who Undergoing Mechanical Ventilation

Study Status: Enrolling by invitation
Recruit Status: Unknown status
Study Type: Interventional

Official Title: the Study of Using Esophageal Pressure to Guide the PEEP Setting in Abdominal Hypertension Patients Who Undergoing Mechanical Ventilation

Brief Summary: Intra-abdominal hypertension can increase the pleural pressure, and then end-expiratory transpulmonary pressures will be turn to negative, Pulmonary atelectasis/acute lung injury/acute respiratory distress syndrome will appear. In the group of people who suffering intra-abdominal hypertension, the investigators use the pressure of esophagus to speculate the Intrathoracic pressure, and to setting PEEP in order to decrease the happening of ALI/ARDS, which may decrease morbidity in this population.

Detailed Summary:
Sponsor: Nanjing Medical University

Current Primary Outcome: ventilator-free days [ Time Frame: 28d ]

Comparison of two groups the duration of ventilation-free in 28d,ventilator-free day include weaning from mechanical ventilation more than 24h.


Original Primary Outcome: Same as current

Current Secondary Outcome: mortality [ Time Frame: 28d ]

28-Day mortality include patients who giving up treatment due to critical condition


Original Secondary Outcome: Same as current

Information By: Nanjing Medical University

Dates:
Date Received: April 2, 2013
Date Started: October 2011
Date Completion: June 2013
Last Updated: April 4, 2013
Last Verified: October 2011