Clinical Trial: Intra-abdominal Hypertension in Critically Ill Patients

Study Status: Recruiting
Recruit Status: Recruiting
Study Type: Observational

Official Title: Intra-abdominal Hypertension in Critically Ill Patients

Brief Summary: The aim of the proposed study is to determine the incidence and prevalence of intra-abdominal hypertension and abdominal compartment syndrome in consecutive intensive care admissions using broad inclusion criteria.

Detailed Summary: Increased pressure within the abdominal cavity is particularly common in intensive care patients and has been shown to be an independent risk-factor for mortality in this patient population. The quoted rates of intra-abdominal hypertension of range anywhere from 20-60% are dependent on the population of patient studied. The prospective observational studies performed to date have been underpowered, used strict inclusion/exclusion criteria or were performed prior to consensus guidelines on the definition and measurement of intra-abdominal pressure and hypertension.
Sponsor: Western University, Canada

Current Primary Outcome: Mortality [ Time Frame: While patient in-hospital, expected stay one week on average ]

As measured prospectively by patient death in the ICU


Original Primary Outcome: Same as current

Current Secondary Outcome:

  • Length of stay [ Time Frame: While patient in-hospital, expected stay one week on average ]
    Measured prospectively from date of admission to ICU to death, or discharge from ICU
  • Abdominal decompression [ Time Frame: While patient in-hospital, expected stay one week on average ]
    Midline laparotomy for abdominal compartment syndrome


Original Secondary Outcome: Same as current

Information By: Western University, Canada

Dates:
Date Received: July 30, 2015
Date Started: September 2015
Date Completion: May 2016
Last Updated: March 1, 2016
Last Verified: March 2016