Clinical Trial: Comparison of Small Colorectal Polyp Removal Using Cold EMR With Hot EMR

Study Status: Not yet recruiting
Recruit Status: Not yet recruiting
Study Type: Interventional

Official Title: Comparison of Small Colorectal Polyp Removal Using Cold Endoscopic Mucosal Resection With Hot Endoscopic Mucosal Resection: a Pilot Study

Brief Summary: This study evaluates the efficacy of small colorectal polyp removal using cold endoscopic mucosal resection with hot endoscopic mucosal resection. Half of the participants will receive cold endoscopic mucosal resection, while the other half will receive hot endoscopic mucosal resection.

Detailed Summary:

Colorectal polyps are considered as precancerous lesions and endoscopical resection is currently the treatment of choice when it is possible.

Colorectal polyps are classified into diminutive polyps (<5mm in diameter), small polyps (6-9mm in diameter), and large polyps (>1cm in diameter). There are several endoscopical treatment methods: cold biopsy forceps polypectomy, cold snare polypectomy, hot biopsy forceps polypectomy, hot snare polypectomy, and endoscopic mucosal resection. Cold polypectomy means mechanical removal of the polyp with snare or biopsy forceps without the use of electrocautery, and hot polypectomy means removal of the polyp with the use of electocautery.


Sponsor: Chonnam National University Hospital

Current Primary Outcome: Complete removal of the colorectal polyp [ Time Frame: At the time of the procedure (endoscopic mucosal resection) ]

The resected specimen will be reviewed microscopically to assess complete resection including the lateral and base margins


Original Primary Outcome: Same as current

Current Secondary Outcome:

  • Procedure time [ Time Frame: At the time of the procedure (endoscopic mucosal resection) ]
    The time needed for the hot EMR vs cold EMR (minutes) will be assessed.
  • Complication after endoscopic mucosal resection [ Time Frame: Within 1 month ]
    Procedure-related complications (bleeding, perforation, and post-coagulation syndrome) will be assessed.


Original Secondary Outcome: Same as current

Information By: Chonnam National University Hospital

Dates:
Date Received: December 20, 2016
Date Started: December 2016
Date Completion: September 2017
Last Updated: December 21, 2016
Last Verified: December 2016