Clinical Trial: Immune Modulation From Trichuris Suis
Study Status: Completed
Recruit Status: Completed
Study Type: Observational
Official Title: Mucosal and Systemic Immune Modulation From Trichuris Suis in a Self-infected Individual
Brief Summary: Mucosal immunology during helminth infection
Detailed Summary: The present study investigates the effects of Trichuris suis on human mucosal and systemic immunity in a single self-infected individual.
Sponsor: University of Aarhus
Current Primary Outcome: Faecal egg excretion [ Time Frame: 15 weeks ]
Original Primary Outcome: Same as current
Current Secondary Outcome:
- Mucosal T cell associated cytokines [ Time Frame: 15 weeks ]Biopsy sampling during established infection
- Systemic immune parameters (eosinophilia, Subtypes of circulating T cells) [ Time Frame: 15 weeks ]Blood samples every week
- Adverse events [ Time Frame: 15 weeks ]Clinical evaluation every week
Original Secondary Outcome: Same as current
Information By: University of Aarhus
Dates:
Date Received: March 9, 2017
Date Started: August 1, 2012
Date Completion:
Last Updated: March 9, 2017
Last Verified: March 2017