Clinical Trial: Prevalence of Metabolic Syndrome in Patients With Intermittent Claudication

Study Status: Completed
Recruit Status: Completed
Study Type: Observational

Official Title: Prevalence of Metabolic Syndrome in Patients With Intermittent Claudication

Brief Summary:

Metabolic syndrome, a group of cardiovascular risk factors related to insulin resistance, is a major determinant of cardiovascular mortality.

Intermittent claudication is a symptom of an early stage of atherosclerosis.

The aim of this study is to determine the prevalence of the metabolic syndrome in patients with intermittent claudication and its correlation with age, gender, localization of arterial obstruction and association with coronary artery disease.

Detailed Summary:

Studies correlating metabolic syndrome and several illnesses are being published, especially affections associated with atherosclerosis, like coronary artery disease, cerebrovascular disease and peripheral arterial disease.

The term peripheral arterial disease, however, refers to several stages of the development of atherosclerosis in the extremities, comprising since asymptomatic patients as far as individuals with critical ischemia.

Intermittent claudication is a symptom of an early stage of atherosclerosis, when medical interventions may still prevent the progression of the disease. Despite the importance of a precocious diagnosis of metabolic syndrome to initiate adequate treatment, its prevalence among these patients is not well determined in the literature.

This is the biggest casuistic in the literature as far as we know.

Sponsor: University of Sao Paulo

Current Primary Outcome: Presence of metabolic syndrome in patients with intermittent claudication [ Time Frame: After laboratory exams results. ]

Original Primary Outcome: Same as current

Current Secondary Outcome: Correlation of metabolic syndrome with age, sex, localization of the arterial obstruction and the association with symptomatic coronary artery disease. [ Time Frame: At the end of data collection ]

Original Secondary Outcome: Same as current

Information By: University of Sao Paulo

Dates:
Date Received: July 23, 2009
Date Started: May 2009
Date Completion:
Last Updated: July 23, 2009
Last Verified: July 2009