Clinical Trial: The Causative Insects in Severe Insect Sting Allergy

Study Status: Completed
Recruit Status: Completed
Study Type: Interventional

Official Title: Evaluating the Causative Insects in the Cases With Severe Insect Sting Allergy

Brief Summary: Study the causative insect by skin prick test and sIgE to wasp, bee and fire ants are important but false positive by crossreactivity can occur. sIgE to recombinant venom allergen is proposed to help in finding the causative insect.

Detailed Summary:

Insect sting allergy from insects in Hymenoptera is not uncommon. The reaction maybe very severe and life threatening. To find the cause of insect sting allergy is important in prevention and specific treatment such as immunotherapy. The skin prick test and sIgE of these insects may have cross reactions so it is difficult to be interpreted.

The usage of sIgE recombinant venom allergen can benefit in separate cross reaction and dual allergy reaction.


Sponsor: Mahidol University

Current Primary Outcome: Mean wheal diameters of skin prick test of local and imported insect allergens [ Time Frame: 12 months ]

Compare Mean wheal diameters of skin prick test of local and imported insect allergens at different concentrations


Original Primary Outcome: Same as current

Current Secondary Outcome: specific IgE level to stinging insect allergen and recombinant venom allergens [ Time Frame: 12 months ]

compare skin prick test result and levels of specific IgE level to stinging insect allergen and recombinant venom allergens


Original Secondary Outcome: Same as current

Information By: Mahidol University

Dates:
Date Received: May 4, 2016
Date Started: February 2015
Date Completion:
Last Updated: May 4, 2016
Last Verified: May 2016