Clinical Trial: Anti-Helicobacter Pylori Antibodies (IgG) in Serum of Women With Unexplained Infertility

Study Status: Completed
Recruit Status: Completed
Study Type: Observational

Official Title: Anti-Helicobacter Pylori Antibodies (IgG) in Serum of Women With Unexplained Infertility

Brief Summary: Prevalence of anti-H.pylori IgG in serum of women with unexplained infertility and comparing that with it's prevalence in fertile women.

Detailed Summary:

Unexplained infertility was diagnosed according to standard World Health Organization (WHO) criteria. All women in the study had hormonal assessment to evaluate their ovulatory cycles, thyroid function, circulating prolactin and androgen levels. The ovarian reserve was checked by measurement of serum FSH and an antral follicle count on the third day of the menstrual cycle. Screening for infertility also included transvaginal ultrasound and hysterosalpingography, to exclude possible uterine malformations or pathologies, and to assess the patency of the fallopian tubes. Male factor infertility was excluded in all couples, according to standard WHO semen analysis.

Following admission, all patients underwent complete clinical examination and detailed medical history was obtained.

A venous sample was collected to test serum for HP IgG seropositivity by enzyme linked immunoassay for HELICOBACTOR PYLORI IgG (ENZYME IMMUNOASSAY TEST KIT).


Sponsor: Ain Shams Maternity Hospital

Current Primary Outcome: Quantitative Helicobacter Pylori IgG Assay in Serum [ Time Frame: 24 hours ]

calculation of quantitative Helicobacter pylori IgG assay in serum


Original Primary Outcome: Presence of anti-Helicobacter Pylori IgG [ Time Frame: 24 hours ]

Presence of anti-Helicobacter Pylori IgG in serum in both groups


Current Secondary Outcome:

Original Secondary Outcome:

Information By: Ain Shams Maternity Hospital

Dates:
Date Received: February 8, 2016
Date Started: March 2015
Date Completion:
Last Updated: April 10, 2016
Last Verified: April 2016