Clinical Trial: The Use of Point-of-Care Ultrasound in the Diagnosis of Acute Infectious Mononucleosis in the Emergency Department

Study Status: Recruiting
Recruit Status: Recruiting
Study Type: Observational

Official Title: The Use of Point-of-Care Ultrasound in the Diagnosis of Acute Infectious Mononucleosis in the Emergency Department

Brief Summary: The purpose of this study is to determine if splenomegaly on point-of-care ultrasound (POCUS) is an accurate and user-friendly surrogate to the heterophile antibody test and Epstein-Barr Virus (EBV) serologies to diagnose acute mononucleosis infection in patients presenting with sore throat to the Emergency Department (ED).

Detailed Summary: The investigators seek to determine whether the presence of splenomegaly on POCUS can accurately diagnose acute infectious mononucleosis in symptomatic ED patients, and determine the feasibility of performing point-of-care ultrasound for splenomegaly by emergency physicians in the emergency department setting.
Sponsor: Jewish General Hospital

Current Primary Outcome: Presence of splenomegaly (maximal splenic cranio-caudal length) on point-of-care ultrasound [ Time Frame: 12 months ]

Splenomegaly is defined as a splenic length of > 11.5 centimetres (cm) for 10-12 year-old patients, > 12 cm for 12-15 year-old patients, > 12 cm for 15-35 year-old female patients, and > 13 cm for 15-35 year-old male patients.


Original Primary Outcome: Presence of splenomegaly (maximal splenic cranio-caudal length) on point-of-care ultrasound [ Time Frame: 12 months ]

Splenomegaly is defined as a splenic length of > 11 centimetres (cm) for 10 year-old patients, > 11.5 cm for 11-12 year-old patients, > 12 cm for 13-15 year-old patients, and > 13 cm for 16-35 year-old patients.


Current Secondary Outcome:

Original Secondary Outcome:

Information By: Jewish General Hospital

Dates:
Date Received: May 31, 2015
Date Started: April 2016
Date Completion: December 2017
Last Updated: August 30, 2016
Last Verified: August 2016