Clinical Trial: Measurement of Energy Metabolism in Infants

Study Status: Recruiting
Recruit Status: Recruiting
Study Type: Observational

Official Title: Measurement of Energy Metabolism in Infants: BabyEE Pilot

Brief Summary: The purpose of this study is to measure energy expenditure during the first 3 months of life in infants.

Detailed Summary:

This study intends to establish the feasibility of undertaking comprehensive metabolic phenotyping in infants. The overarching aim is to complete a prospective assessment of energy expenditure in the new infant metabolic chamber approximately one week apart to determine the accuracy and precision of infant protocols related to energy metabolism (sleeping metabolic rate, resting metabolic rate, diet-induced thermogenesis), physical activity, and sucking behavior. This cross-sectional study will answer the following questions:

  1. What is the test re-test reliability of measuring energy expenditure (sleeping metabolic rate, resting metabolic rate, diet-induced thermogenesis) in an infant under the same conditions, 5-7 days apart?
  2. What is the reliability of 24h energy expenditure estimated by the infant metabolic chamber in comparison to a 7-day doubly labeled water study?
  3. How do energy expenditure measurements in infants need to be adjusted to account for variability in infant size and body composition?

Sponsor: Pennington Biomedical Research Center

Current Primary Outcome: Energy Expenditure [ Time Frame: Between 1 and 3 months of age ]

Infant metabolic chamber and doubly labeled water


Original Primary Outcome: Same as current

Current Secondary Outcome: Infant sucking behavior [ Time Frame: Between 1 and 3 months of age ]

Neonur device used on an infant bottle


Original Secondary Outcome: Same as current

Information By: Pennington Biomedical Research Center

Dates:
Date Received: January 14, 2016
Date Started: February 2016
Date Completion: December 2017
Last Updated: April 19, 2017
Last Verified: April 2017