Clinical Trial: Use of Propranolol Hydrochloride in the Treatment of Metastatic STS

Study Status: Not yet recruiting
Recruit Status: Not yet recruiting
Study Type: Interventional

Official Title: The Use of Propranolol Hydrochloride Combined With Anthracyclin Based Chemotherapy in the Treatment of Metastatic Soft Tissue Sarcoma

Brief Summary:

Fifty patients with pathological proof of malignant soft tissue sarcoma will receive Anthracyclin based chemotherapy combined with propranolol 40 mg twice daily.

  • The primary end point : To assess Progression Free Survival (PFS)
  • The secondary end points : To assess Overall Survival (OS) and Toxicity Profile

Detailed Summary:
Sponsor: Ain Shams University

Current Primary Outcome: Progression Free Survival [ Time Frame: an average of 1 year ]

Progression free survival (PFS) is defined as the time interval between the dates of first treatment administration and first observation of PD.


Original Primary Outcome: Same as current

Current Secondary Outcome: Overall Survival [ Time Frame: an average of 3 years ]

Overall Survival (OS) is defined as the time from the date of the first treatment administration to the date of death due to any cause.


Original Secondary Outcome: Same as current

Information By: Ain Shams University

Dates:
Date Received: March 16, 2017
Date Started: August 30, 2017
Date Completion: August 30, 2019
Last Updated: April 5, 2017
Last Verified: April 2017