Clinical Trial: Utilization of iMRI for Transsphenoidal Resection of Pituitary Macroadenomas
Study Status: Recruiting
Recruit Status: Recruiting
Study Type: Interventional
Official Title:
Brief Summary: The investigators are studying the utility of intra-operative magnetic resonance imaging (iMRI) during transsphenoidal pituitary surgery by randomizing patients to either an intra-operative MRI after resection, or no intra-operative MRI. The investigators will then count the number of gross total resection in each group of patients and also the complications related to surgery.
Detailed Summary:
Sponsor: Dartmouth-Hitchcock Medical Center
Current Primary Outcome: Gross total resection [ Time Frame: 24 hours after surgery ]
Original Primary Outcome: Same as current
Current Secondary Outcome:
- Operative time [ Time Frame: intraoperative ]
- Endocrine function, specifically serum levels of TSH, morning cortisol, sodium, somatomedin, FH, LSH, and documented need for desmopressin [ Time Frame: 30 days post-op ]TSH level, morning cortisol level, documented need for desmopressin, sodium level, somatomedin level, FH level, LSH level
- CSF leak [ Time Frame: 30 days post-op ]
- Readmission [ Time Frame: 30 days post-op ]
Original Secondary Outcome: Same as current
Information By: Dartmouth-Hitchcock Medical Center
Dates:
Date Received: March 5, 2015
Date Started: March 2015
Date Completion:
Last Updated: January 20, 2016
Last Verified: January 2016
