Clinical Trial: Effect of W-3 Polyunsaturated Fatty Acids on Serum Albumin Concentration in Patients With Acute Heart Failure, Hypoalbuminemia, and High Inflammatory Activity

Study Status: Recruiting
Recruit Status: Recruiting
Study Type: Interventional

Official Title: Effect of W-3 Polyunsaturated Fatty Acids on Serum Albumin Concentration in Patients With Acute Heart Failure, Hypoalbuminemia, and High Inflammatory Activity

Brief Summary: Assess whether high doses of ?-3 fatty acids added to standard treatment of patients with acute hearta failure, hypoalbuminemia and high inflammatory activity, promotes an increase in serum albumin

Detailed Summary:

Assess whether high doses of ?-3 fatty acids added to standard treatment of patients with acute hearta failure, hypoalbuminemia and high inflammatory activity, promotes an increase in serum albumin

Assess the effect of high doses of ?-3 fatty acids added to standard treatment of patients with acute hearta failure, hypoalbuminemia and high inflammatory activity on:

  • Inflammatory activity (C-reactive protein)
  • The development of biomarkers (NTproBNP).
  • The prognosis of patients evaluated by the combined event of death from any cause or readmission for heart failure within three months after randomization.

Sponsor: Hospital San Juan de la Cruz

Current Primary Outcome: Serum albumin levels [ Time Frame: Four weeks ]

Serum albumin levels in the fourth week


Original Primary Outcome: Same as current

Current Secondary Outcome:

  • C-reactive protein levels [ Time Frame: Four weeks ]
    C-reactive protein levels in the fourth week
  • NTproBNP levels [ Time Frame: Four weeks ]
    NTproBNP levels in the fourth week
  • Combined event of death from any cause or readmission for heart failure [ Time Frame: Three months ]
    Combined event of death from any cause or readmission for heart failure within three months after randomization


Original Secondary Outcome: Same as current

Information By: Hospital San Juan de la Cruz

Dates:
Date Received: March 6, 2016
Date Started: March 2016
Date Completion: March 2017
Last Updated: March 10, 2016
Last Verified: March 2016