Clinical Trial: Early Prediction of Hypocalcaemia Following Thyroid Surgery

Study Status: Completed
Recruit Status: Completed
Study Type: Interventional

Official Title: Early Prediction of Hypocalcaemia Following Thyroid Surgery: A Prospective Randomized Clinical Trial

Brief Summary: 150 patients divided into two groups.The experimental group was submitted at the assay of iPTH six hours after surgery whilst the control group was submitted to a daily assay of serum calcium and phosphorus.

Detailed Summary:

Purpose: The aim of this randomized controlled trial was to validate the results of a previous prospective cohort study conducted in the same surgical unit regarding the use of concomitant intact parathyroid hormone (iPTH) and serum calcium measurement in predicting hypocalcemia after total thyroidectomy.

Methods: From January 2014 to January 2015, 150 patients underwent total thyroidectomy in our department and were divided into two groups. The experimental group was submitted at the assay of iPTH six hours after surgery whilst the control group was submitted to a daily assay of serum calcium and phosphorus. Sensitivity and specificity of different serum measurements have been calculated using the Receiver-operator characteristics (ROC) curve.


Sponsor: University of Cagliari

Current Primary Outcome: Sensibility and specificity of iPTH and serum calcium measurement [ Time Frame: 1 month ]

Sensitivity and specificity of serum measurement using the Receiver-operator characteristics (ROC) curve


Original Primary Outcome: Same as current

Current Secondary Outcome:

Original Secondary Outcome:

Information By: University of Cagliari

Dates:
Date Received: May 6, 2016
Date Started: January 2014
Date Completion:
Last Updated: July 29, 2016
Last Verified: July 2016