Clinical Trial: Effect of Valsartan on Left Ventricular Myocardial Functions in Hypertensive Patients With Left Ventricular Hypertrophy
Study Status: Completed
Recruit Status: Completed
Study Type: Interventional
Official Title: Effect of Valsartan on Left Ventricular Myocardial Functions in Hypertensive Patients With Left Ventricular Hypertrophy
Brief Summary: The study hypothesis: Valsartan as an angiotensin II receptor blocker treatment has beneficial effects on both midwall mechanics and myocardial functions in hypertensive patients with Left ventricular hypertrophy.
Detailed Summary:
Sponsor: Mustafa Kemal University
Current Primary Outcome: change from baseline in midwall fractional shortening (mFS) and tissue Doppler systolic wave (Sm) measured by echocardiography at six months [ Time Frame: six months ]
Original Primary Outcome: Same as current
Current Secondary Outcome:
- change from baseline in systolic and diastolic blood pressure at six months [ Time Frame: six months ]
- change from baseline in left ventricular mass index measured by echocardiography at six months [ Time Frame: six months ]
Original Secondary Outcome: Same as current
Information By: Mustafa Kemal University
Dates:
Date Received: August 18, 2011
Date Started: November 2006
Date Completion:
Last Updated: August 29, 2011
Last Verified: August 2011
