Clinical Trial: Effect of Extracorporeal Shock Waves on Hypertrophy Scar

Study Status: Not yet recruiting
Recruit Status: Not yet recruiting
Study Type: Interventional

Official Title: Assessment of the Effect of Extracorporeal Shock Waves on Hypertrophy Scar

Brief Summary: Assess the effect of extracorporeal shock waves on hypertrophy scar

Detailed Summary:

Prolonged and abnormal scarring after trauma, burns and surgical procedures often results in functional and cosmetic deformities. A wide variety of treatments have been advocated for pathologic scars regression. Unfortunately, the reported efficacy has been variable.Unfocused extracorporeal shock wave therapy is a feasible and non-intensive treatment. And it is an emerging option for the treatment of painful and retracting scars.

Administration of ESWT appears to result in significant improvements in scar clinical appearance, mobility and subjective pain. Clinical data were mirrored by histologic changes in connective tissue appearance and scar vascularization. Extracorporeal shock wave therapy is also an effective and conservative treatment for patients with aesthetic and functional sequela from burn scars. It is a feasible, cost-effective, well-tolerated treatment that can be used in the management of post-burn pathologic scars after the patients are briefed on the practical aspects of the treatment procedure.


Sponsor: Mackay Memorial Hospital

Current Primary Outcome: change from baseline thick of scar [ Time Frame: immediately post intervention, 1 month after, and 3 months ]

sonography for thick of scar


Original Primary Outcome: Same as current

Current Secondary Outcome:

  • change from baseline Modified Vancouver Scar Scale [ Time Frame: immediately post intervention, 1 month after, and 3 months ]
    questionnaires of Modified Vancouver Scar Scale for scar measure
  • change from baseline Visual analogue scores (VAS) [ Time Frame: immediately post intervention, 1 month after, and 3 months ]
    Visual analogue scores (VAS) for pain
  • change from baseline skin color [ Time Frame: immediately post intervention, 1 month after, and 3 months ]
    DermaLab Combo series for skin color
  • change from baseline Patient Scar Assessment Scale (POSAS) [ Time Frame: immediately post intervention, 1 month after, and 3 months ]
    questionnaires of Patient Scar Assessment Scale (POSAS) for scar measure


Original Secondary Outcome: Same as current

Information By: Mackay Memorial Hospital

Dates:
Date Received: April 19, 2017
Date Started: June 1, 2017
Date Completion: June 1, 2019
Last Updated: April 27, 2017
Last Verified: April 2017