Clinical Trial: Renal Atherosclerotic Revascularization Evaluation: RAVE Study
Study Status: Completed
Recruit Status: Completed
Study Type: Interventional
Official Title:
Brief Summary: The RAVE study will compare renal revascularization to medical management for people with atherosclerotic renal vascular disease (ARVD) and the indication for revascularization.
Detailed Summary: It is uncertain whether patients with renal vascular disease will have renal or mortality benefits from re-establishing renal blood flow with renal revascularization procedures. Patients will be assessed for the standard nephrology research outcomes of progression to doubling of creatinine, need for dialysis, and death, as well as other cardiovascular outcomes. The investigators will also establish whether the use of a new inexpensive, simple and available ultrasound test, the renal resistance index (RRI), can identify patients with renal vascular disease who will not benefit from renal revascularization procedures.
Sponsor: Sunnybrook Health Sciences Centre
Current Primary Outcome:
- Dialysis
- Death
- Doubling of creatinine
Original Primary Outcome: Same as current
Current Secondary Outcome:
Original Secondary Outcome:
Information By: Sunnybrook Health Sciences Centre
Dates:
Date Received: August 4, 2005
Date Started: January 2005
Date Completion: December 2006
Last Updated: January 8, 2007
Last Verified: February 2006
