Clinical Trial: Simvatstatin Used to Treat Pulmonary Hypertension
Study Status: Terminated
Recruit Status: Unknown status
Study Type: Interventional
Official Title: the Clinical Research Using Simvastatin as a Medication to Treat Advanced Secondary Pulmonary Hypertension
Brief Summary: we try to use simvastatin in the treatment of advanced pulmoary hypertension secondary to congenital heart disease or chronic pulmonary embolism before and after the operation.
Detailed Summary: advanced pulmonary hypertension is refractory to the medication in use nowaday, especially pulmonary hypertension secondary to congenital heart disease or chronic pulmonary embolism.It is revealed that statins may intefere the pathogenisis of the pulmonary hypertension in many key poing, such as improving apotosis or inhiting the proliferation of pulmonary vascular smooth muscle cell. so we try to use simvastatin in the treatment of advanced pulmoary hypertension secondary to congenital heart disease or chronic pulmonary embolism before and after the operation.
Sponsor: Capital Medical University
Current Primary Outcome:
- the simvastatin can alleviate pulmonary hypertension
- pulmonary pressure
Original Primary Outcome: Same as current
Current Secondary Outcome: simvastatin can highten the perioperative and long term survaval rate and the living quality
Original Secondary Outcome: Same as current
Information By: Capital Medical University
Dates:
Date Received: October 1, 2007
Date Started: January 2009
Date Completion: January 2012
Last Updated: October 1, 2007
Last Verified: September 2007
