Clinical Trial: Immune Responses to BCG Vaccination in Malawi and the UK

Study Status: Completed
Recruit Status: Completed
Study Type: Interventional

Official Title:

Brief Summary: BCG vaccination has been found to provide greater protection against TB in the UK than in Malawi. This study compares immune responses in BCG-vaccinated and unvaccinated teenagers and young adults in Malawi and in the UK.

Detailed Summary:
Sponsor: London School of Hygiene and Tropical Medicine

Current Primary Outcome:

• Delayed-type hypersensitivity
• cytokine responses (eg IFNg) to mycobacterial antigens

Original Primary Outcome: Same as current

Current Secondary Outcome: scar size

Original Secondary Outcome: Same as current

Information By: London School of Hygiene and Tropical Medicine

Dates:
Date Received: October 17, 2005
Date Started:
Date Completion:
Last Updated: December 14, 2005
Last Verified: December 2002