Clinical Trial: Identification of Gene Biomarkers in Aging Skin

Study Status: Completed
Recruit Status: Completed
Study Type: Observational

Official Title: Identification of Gene Biomarkers in Aging Skin; a Blinded, Prospective, Single-center, Clinical Study

Brief Summary: This study is a blinded, prospective, single-center, clinical study conducted in Japanese female subjects between the ages of 20-75 years. This design uses skin biopsy samples from environmentally exposed areas and unexposed (control) areas within the same subjects to assess the gene expression profile from three different age groups.

Detailed Summary: The primary objective of the skin aging study is to investigate changes in gene expression patterns that occur during the aging process.
Sponsor: Interleukin Genetics, Inc.

Current Primary Outcome: The primary objective of the study is to investigate changes in gene expression patterns that occur during the aging process. A significant fold change in differential gene expression will be >1.5 and an adjusted p-value of <0.05. [ Time Frame: 1 year ]

Original Primary Outcome: Same as current

Current Secondary Outcome: Secondary outcome measures are the evaluation of genetic expression changes in sun-protected and sun-exposed skin and an investigation of their biological pathways. [ Time Frame: 1 year ]

Original Secondary Outcome: Same as current

Information By: Interleukin Genetics, Inc.

Dates:
Date Received: April 20, 2009
Date Started: August 2008
Date Completion:
Last Updated: March 30, 2015
Last Verified: October 2009