Clinical Trial: Protective Effects of Normobaric Hyperoxia on Blood Brain Barrier in Patients With Acute Ischemic Stroke
Study Status: Not yet recruiting
Recruit Status: Not yet recruiting
Study Type: Interventional
Official Title: The Effect of Normobaric Hyperoxia on Blood Brain Barrier in AIS Patients Based on a Blood Marker for the Evaluation of Blood Brain Barrier Damage From Animal Experiments
Brief Summary: The purpose of this study is to find out a serum marker for the evaluation of blood brain barrier damage based on animal experiments and investigate the effect of NBO（Normobaric hyperoxia）on blood brain barrier in the acute ischemic stroke patients who received r-tPA thrombolytic therapy.
Detailed Summary:
Sponsor: Capital Medical University
Current Primary Outcome:
- levels of blood biomarkers [ Time Frame: 7days ]a serum marker for the evaluation of blood brain barrier damage based on animal experiments
- Scores assessed by National Institutes of Health Stroke Scale(NIHSS) [ Time Frame: 7days ]
Original Primary Outcome: Same as current
Current Secondary Outcome: Number of participants with adverse events that are related to treatment [ Time Frame: 7days ]
Original Secondary Outcome: Same as current
Information By: Capital Medical University
Dates:
Date Received: November 23, 2016
Date Started: December 2016
Date Completion: March 2017
Last Updated: November 23, 2016
Last Verified: November 2016
