Clinical Trial: Prevalence Of Hyperhomocysteinemia In Thai Chronic Kidney Disease (CKD) Patients

Study Status: Completed
Recruit Status: Completed
Study Type: Observational

Official Title: Prevalence Of Hyperhomocysteinemia In Thai CKD Patients And Relationship To Cardiovascular Events: Subgroup Analysis From Thai SEEK Study

Brief Summary: It is well recognized that patients with chronic kidney disease (CKD) have an increased risk for cardiovascular disease (CVD) and hyperhomocysteinemia appears to be a predictor of future CVD events. Hyperhomocysteinemia has been reported to bo of high prevalence in patients with CKD. The investigators aim to study the prevalence of hyperhomocysteinemia in Thai CKD patients by using Thai Screening and Early Evaluation of Kidney Disease (SEEK) study database and their relationship to CVD.

Detailed Summary: Ninety eight subjects were sampling from Thai SEEK study database Traditional Traditional risk factors of CVD such as total cholesterol, triglyceride, age, sex, history of smoking and blood pressure levels were examined and recorded. Stored sera of these subjects were analyzed for the total homocysteine (tHcy) level. Analysis of variance was used to evaluate the different of mean tHcy among groups
Sponsor: Bangkok Metropolitan Administration Medical College and Vajira Hospital

Current Primary Outcome: Level of Homocysteine [ Time Frame: 3 months ]

Level of homocysteinemia according to each CKD level


Original Primary Outcome: Same as current

Current Secondary Outcome: Association of cardiovascular event to the level of homocysteine [ Time Frame: 3 months ]

Hugh level of homocysteine will have association with cardiovascular events or not


Original Secondary Outcome: Same as current

Information By: Bangkok Metropolitan Administration Medical College and Vajira Hospital

Dates:
Date Received: July 8, 2011
Date Started: June 2010
Date Completion:
Last Updated: July 11, 2011
Last Verified: May 2010