Clinical Trial: Assessing the Impact of a Mode of Vitamin D Supplementation (Sequential Dose vs Daily Dose) on the Incidence of Hypercalciuria in Children Aged From 2 to 6 Years

Study Status: Not yet recruiting
Recruit Status: Not yet recruiting
Study Type: Interventional

Official Title:

Brief Summary: Recommendations for vitamin D supplementation for children between 2 and 6 years offer strong sequential doses of vitamin D: 2 times 100 000 units in spaced winter period of 3 months. Data from the literature show a further increase in the incidence of oxalo-calcium stones in children and adolescents associated with hypercalciuria with training Randall plates, essential step lithogenesis calcium oxalate. Knowing the links between vitamin D and urinary calcium excretion, these data lead to the question of increased sensitivity in some children with vitamin D, sensitivity could explain these situations with hypercalciuria increase the gallstone risk. This increased sensitivity to vitamin D may unmask particularly if inputs of high doses of vitamin responsible then a transient hypercalciuria with development of microcrystals.

Detailed Summary:
Sponsor: University Hospital, Montpellier

Current Primary Outcome: Changes from calcium level in urines at day 7, day 14 and day 28 [ Time Frame: day 7, day 14 and day 28 ]

Original Primary Outcome: Same as current

Current Secondary Outcome:

Original Secondary Outcome:

Information By: University Hospital, Montpellier

Dates:
Date Received: November 7, 2016
Date Started: December 2016
Date Completion: December 2018
Last Updated: November 28, 2016
Last Verified: November 2016