Clinical Trial: Hypercalciuria and Calcium Stone Disease in Caucasian Patients

Study Status: Available
Recruit Status: Available
Study Type: Expanded Access

Official Title: Hypercalciuria and Calcium Stone Disease in Caucasian Patients

Brief Summary: The hypothesis of this study proposal is that pediatric urinary stone formers have genetic risk factors which predispose their urinary stone production. 50-60% of pediatric stone patients have a positive family history of urinary stone disease. Several genetic mutations have been identified which predispose patients to various types of urinary stones. These genetic mutations can also lead to other significant sequela besides stones, including osteopenia/osteoporosis (bone loss). Furthermore, metabolic abnormalities can be identified in more than 50% of pediatric stone formers, some of which can be improved/alleviated with medical intervention to help decrease rate of stone formation and the need for hospitalization and surgical intervention.

Detailed Summary:
Sponsor: University of Texas Southwestern Medical Center

Current Primary Outcome:

Original Primary Outcome:

Current Secondary Outcome:

Original Secondary Outcome:

Information By: University of Texas Southwestern Medical Center

Dates:
Date Received: September 30, 2008
Date Started:
Date Completion:
Last Updated: October 30, 2008
Last Verified: October 2008