Clinical Trial: Effects of Music Therapy on Huntington's Disease
Study Status: Completed
Recruit Status: Completed
Study Type: Interventional
Official Title: The Effects of Music Therapy on Depression, Chorea and Other Symptoms of Huntington's Disease
Brief Summary: The purpose of this study is primarily to assess the ability of a music therapy program to improve holistically the psychological, somatic, and social symptoms of patients with Huntington 's disease (HD). We hope to demonstrate the benefits of applying music therapy interventions to the management methods of HD, thus paving the way for the development of an effective music therapy program for individuals with HD.
Detailed Summary:
ABSTRACT
Background: Recent studies show that music therapy helps improve the symptomatic manifestations of Parkinson's Disease. Few studies have looked at music therapy as a treatment for the psychiatric, cognitive and motor symptoms of patients with Huntington's disease (HD).
Objective: To examine the feasibility and tolerability of a treatment program of music therapy for patients with Huntington's disease. Also, to determine if music therapy improves the mood and motor features of HD while improving quality of life.
Methods: Subjects with HD were recruited to participate in a six-week study that included one individual, half-hour music therapy session and one hour-long group session per week. The music therapy protocols were adapted from the Colorado State University's Neurological Music Therapy program and were targeted to HD symptoms including balance and posture, fine motor skills, memory and attention, vocalizations, and mood. In particular the protocols included Rhythmic Auditory Stimulation (RAS), Pattern Sensory Enhancement (PSE), and Therapeutic Instrumental Music Playing (TIMP). Primary outcome of tolerability was to be assessed by the subjects' adherence to the therapeutic protocol, attendance, and the results of an exit survey inquiring about their feelings toward the use of music therapy in HD. A secondary outcome of the study was the change in the Unified Huntington's Disease Rating Scale (UHDRS) score between baseline and study completion.
Results: Five subjects were recruited for study participation (one female and four males). Music therapy was found to be a tolerable and feasible treatment for patients with HD (100% adherence and 98% attendance). Exit surveys demonstrated strongly positive feelings towar
Sponsor: University of Rochester
Current Primary Outcome: To examine the feasibility and tolerability of a treatment program of MT for subjects with HD. [ Time Frame: End of Study ]
Original Primary Outcome: To examine the feasibility and tolerability of a treatment program of MT for subjects with HD.
Current Secondary Outcome: To determine if MT improves the mood and motor features of HD while improving quality of life. [ Time Frame: End of study ]
Original Secondary Outcome: To determine if MT improves the mood and motor features of HD while improving quality of life.
Information By: University of Rochester
Dates:
Date Received: September 12, 2005
Date Started: July 2004
Date Completion:
Last Updated: August 19, 2011
Last Verified: August 2011
