Clinical Trial: A Trial on Probiotics in Preventing Hirschsprung's Disease Associated Entercolitis

Study Status: Completed
Recruit Status: Completed
Study Type: Interventional

Official Title: A Prospective Multicenter Randomized Controlled Trial on Probiotics in Preventing Hirschsprung's Disease Associated Entercolitis

Brief Summary: Enterocolitis(EC) is the most common and serious postoperative complication of Hirschsprung's disease(HD) with high morbidity and mortality. Probiotics are live microbes that, when administered in adequate amounts, confer health benefit to the host.Based on this previous knowledge on the beneficial effects of probiotics during pro-inflammatory conditions of the gastrointestinal tract, investigators hypothesized that oral probiotics could decrease the incidence and severity of Hirschsprung's disease associated enterocolitis(HAEC).Investigators conducted a prospective, multicenter, randomized and controlled trial to assess whether oral probiotics could decrease the incidence and severity of Hirschsprung's disease associated enterocolitis(HAEC).

Detailed Summary:
Sponsor: Tongji Hospital

Current Primary Outcome: Probiotics Prevent Hirschsprung's Disease Associated Entercolitis [ Time Frame: two years ]

Original Primary Outcome: Same as current

Current Secondary Outcome:

Original Secondary Outcome:

Information By: Tongji Hospital

Dates:
Date Received: August 21, 2013
Date Started: January 2008
Date Completion:
Last Updated: August 29, 2013
Last Verified: August 2013