Clinical Trial: Sequelae of Developmental Dysplasia of the Hip

Study Status: Recruiting
Recruit Status: Recruiting
Study Type: Observational

Official Title: Structural and Functional Sequelae of Developmental Dysplasia of the Hip

Brief Summary: The aim of this study is to assess long term effects of developmental dysplasia of the hip (DDH) to overall health and quality of life later in life. We compare hip radiographs, hip symptoms, clinical examination, head asymmetry, dental examination and intraoral scans of 170 children and young adults treated for DDH in their childhood with age and sex matched controls.

Detailed Summary:

Developmental dysplasia of the hip (DDH) is the most common musculoskeletal disorder in infancy. However there are few reports of long term effects of successfully treated DDH. Incidence of DDH in neonatal period is approximately 1-10/1000 depending on screening protocols used, the age of the infant during screening and which ultrasonographic findings are considered normal and which DDH. The prevalence of hip dysplasia in adult population is grossly 4 % when using Wibergs Center Edge (CE) ≤ 20° as definition of dysplasia. It is still unclear, what is the relation between adult acetabular dysplasia and developmental dysplasia in children. Hip dysplasia overall is a major contributing factor in hip osteoarthrosis and total hip replacement in young adults.

The aim of this study is to assess long term effects of developmental dysplasia of the hip to overall health and quality of life later in life. We compare hip radiographs, hip symptoms, clinical examination, head asymmetry, dental examination and intraoral scans of 170 children and young adults treated for DDH in their early childhood with age and sex matched controls.


Sponsor: University of Oulu

Current Primary Outcome: Wibergs Centre-Edge Angle [ Time Frame: 10 - 30 years after DDH has been treated ]

Original Primary Outcome: Same as current

Current Secondary Outcome:

  • The Copenhagen Hip and Groin Outcome Score (HAGOS) [ Time Frame: 10 - 30 years after DDH has been treated ]
  • Oral Heath Impact Profile [ Time Frame: 10 - 30 years after DDH has been treated ]
    Oral Heath Impact Profile (OHIP-14) -questionaire to assess Oral Health-related Quality of Life
  • Occlusal asymmetries [ Time Frame: 10 - 30 years after DDH has been treated ]
    Determined by dental examination and intraoral scan
  • Presence of facial asymmetry [ Time Frame: 10 - 30 years after DDH has been treated ]
    Determined by 3D -photogrammetric images


Original Secondary Outcome: Same as current

Information By: University of Oulu

Dates:
Date Received: April 20, 2015
Date Started: January 2016
Date Completion: December 2026
Last Updated: May 3, 2017
Last Verified: May 2017