Clinical Trial: Trial Comparing Efficacy of Treatments for Hidradenitis Suppurativa
Study Status: Recruiting
Recruit Status: Unknown status
Study Type: Interventional
Official Title: Randomized Control Trial Comparing Efficacy of Antibiotic Therapy Alone Versus Antibiotic Therapy in Conjunction With Quadruple Pulse Therapy Using NdYag Laser in Treatment of Hi
Brief Summary: The purpose of this research study is to further evaluate the efficacy of two treatment regimens for the treatment of hidradenitis suppurativa. This is a randomized controlled study. Patients will be randomly assigned to an arm of the study.
Detailed Summary: Histological studies suggest that HS is a disease of the follicles with apocrine involvement as a secondary event. The investigators have identified in a previous study that the Nd Yag laser is highly effective for decreasing the inflammation, pain, suppuration and frequency of recurrence of HS. Oral antibiotic therapy with Clindamycin and Rifampin has also been reported in previous studies to be a highly effective treatment regimen for HS and is commonly used by physicians in medical management of HS. The investigators would like to compare the efficacy of NdYag laser treatment combined with antibiotics versus treatment with antibiotics alone. The goal is to evaluate the success of these two treatment regimens on existent HS lesions as well as prevention of recurrence. There will be approximately 18 people in this research study at Henry Ford Health System (HFHS).
Sponsor: Henry Ford Health System
Current Primary Outcome: Number and severity of lesions [ Time Frame: 5 total clinic visits over 6 month period ]
Original Primary Outcome: Efficacy of treatment [ Time Frame: 5 total clinic visits over 6 month period consisting of an initial visit, a visit at 4 weeks after the initial visit, a visit at 8 weeks, a visit at 10 weeks and a visit at 6 months. ]
Current Secondary Outcome:
- Change in quality of life during treatment [ Time Frame: 5 total clinic visits over 6 month period ]
- Recurrence of disease [ Time Frame: 5 total clinic visits over 6 month period ]
Original Secondary Outcome:
- Change in quality of life during treatment [ Time Frame: 5 total clinic visits over 6 month period consisting of an initial visit, a visit at 4 weeks after the initial visit, a visit at 8 weeks, a visit at 10 weeks and a visit at 6 months. ]
- Recurrance of disease [ Time Frame: 5 total clinic visits over 6 month period consisting of an initial visit, a visit at 4 weeks after the initial visit, a visit at 8 weeks, a visit at 10 weeks and a visit at 6 months. ]
Information By: Henry Ford Health System
Dates:
Date Received: February 2, 2010
Date Started: February 2010
Date Completion: December 2013
Last Updated: March 27, 2013
Last Verified: March 2013
