Clinical Trial: Dexamethasone-induced Hiccup in Chemotherapy Patients Treated by Methylprednisolone Rotation

Study Status: Completed
Recruit Status: Completed
Study Type: Interventional

Official Title: Antiemetic Corticosteroid Rotation From Dexamethasone to Methylprednisolone to Prevent Dexamethasone-Induced Hiccup in Cancer Patients Treated With Chemotherapy: A Randomi

Brief Summary: The aims of this study were to investigate the feasibility of methylprednisolone rotation as treatment of DIH.

Detailed Summary: we planned a randomized prospective trial for cancer patients with DIH. The objective of the present study was to determine whether the rotation of corticosteroids affects the incidence and intensity of DIH without compromising the antiemetic efficacy.
Sponsor: Chung-Ang University

Current Primary Outcome: The intensities of hiccups [ Time Frame: 2 months ]

Clinically assessed every cycles(2-4weeks). The intensities of hiccups were assessed using a NRS.


Original Primary Outcome: Same as current

Current Secondary Outcome: The intensities of emesis [ Time Frame: 2 months ]

CLinically assessed every cycles (2-4weeks) The intensities of emesis were assessed using a NRS.


Original Secondary Outcome: Same as current

Information By: Chung-Ang University

Dates:
Date Received: October 28, 2013
Date Started: October 1, 2013
Date Completion:
Last Updated: April 27, 2017
Last Verified: April 2017