Clinical Trial: Efficacy and Safety of Foscarnet Sodium and Sodium Chloride Injection in Patients With Herpes Zoster

Study Status: Completed
Recruit Status: Unknown status
Study Type: Interventional

Official Title: A Multi-centered, Randomized Study to Evaluate the Efficacy and Safety of Foscarnet Sodium and Sodium Chloride Injection Compared to Intravenous Acyclovir in Patients With Herpes

Brief Summary: The purpose of this study is to evaluate the efficacy and safety of Foscarnet Sodium and Sodium Chloride Injection in patients with herpes zoster, and observe incidence of Postherpetic neuralgia

Detailed Summary:
Sponsor: Cttq

Current Primary Outcome: Effective rate [ Time Frame: 8th days ]

Effective rate = (No. of patients achieving recovery+ markedly improvement)/Total patients No.×100%.

Recovery: curative index≥90%; Markedly improved: curative index 60%-89%; Improved: curative index 20%-59%; Ineffective: curative index＜20%. Where Curative Index= (patient's pre-treatment condition score - post-treatment condition score)/pre-treatment condition score ×100%



Original Primary Outcome: Same as current

Current Secondary Outcome:

  • Incidence of Postherpetic neuralgia [ Time Frame: 3rd month ]
  • number of participants with adverse event and serious adverse event [ Time Frame: up to 3 months ]


Original Secondary Outcome: Same as current

Information By: Cttq

Dates:
Date Received: May 28, 2014
Date Started: May 2014
Date Completion:
Last Updated: May 28, 2014
Last Verified: May 2014