Clinical Trial: Laparoscopic Intraperitoneal Mesh Repair of Ventral Hernia: Comparison to Conventional Mesh Repair

Study Status: Completed
Recruit Status: Completed
Study Type: Interventional

Official Title:

Brief Summary: The laparoscopic repair of ventral hernias is still a controversial therapeutic option. To evaluate the efficacy and safety of laparoscopic repair we compare the results of the open and laparoscopic repair of ventral hernia,. 53 patients were undergo laparoscopic or open repair of ventral hernia . All defects were estimated to be larger than 5 cm in diameter. Twenty six patients underwent attempted laparoscopic ventral hernia repair (LVHR) with mesh and twenty seven patients underwent open ventral hernia repair (OVHR) with mesh

Detailed Summary:

Between March 2003 and December 2004, 53 patients (16 males and 37 females) with ventral hernias were treated by a laparoscopic or open approach. Patients were divided into two groups: one group underwent laparoscopic repair with GORE-TEX Dual Mesh, and the other group underwent open repair with proline mesh. Informed written consents were obtained from all patients.

Inclusion criteria involved any patient aged over 30 years, medical fitness for general anesthesia, the absence of coagulopathy, and hernial defect ≥ 5 cm in any dimension or recurrent hernias. Exclusion criteria were neoplastic patients, immune compromised patients, mentally incompetent patients and those who refused to give signed consents.

Demographic features, operative details and postoperative outcomes were collected prospectively and included patient age, gender, body mass index (BMI) (weight in kg/height in m2), number of prior abdominal operations, number of previous hernia repairs, technique of repair, size of facial defect, type of prosthetic mesh, operating time, conversion rate, length of hospital stay, operative and postoperative complications, and hernia recurrences.

Thirty-seven patients presented with an incisional hernia (12 upper midline, 15 lower midline, and 10 transverse abdominal), 8 had an epigastric hernia, 8 had an periumbilical hernia, . All defects were estimated to be larger than 5 cm in diameter.

Standard bowel preparation was undertaken for every patient on the day before the operation. Prophylactic short-term antibiotic therapy with a one gram of third-generation cephalosporin was also administered routinely two hours before the operation. Nasogastric suction and bladder catheterization were used routinely during the operati
Sponsor: Mansoura University

Current Primary Outcome:

Original Primary Outcome:

Current Secondary Outcome:

Original Secondary Outcome:

Information By: Mansoura University

Dates:
Date Received: September 20, 2007
Date Started: March 2003
Date Completion:
Last Updated: September 20, 2007
Last Verified: September 2007