Clinical Trial: Effect of Transjugular Intrahepatic Portosystemic Shunt on Oxygenation in Cirrhotic Patients With Hepatopulmonary Syndrome

Study Status: Terminated
Recruit Status: Unknown status
Study Type: Observational

Official Title: Effect of Transjugular Intrahepatic Portosystemic Shunt on Oxygenation in Cirrhotic Patients With Hepatopulmonary Syndrome

Brief Summary: To prospectively investigate the effect of transjugular intrahepatic portosystemic shunt (TIPS) on oxygenation in cirrhotic patients with hepatopulmonary syndrome (HPS).

Detailed Summary:
Sponsor: West China Hospital

Current Primary Outcome: Alveolar-arterial oxygen gradient (PA-a,O2) [ Time Frame: 12 Weeks ]

Original Primary Outcome: Same as current

Current Secondary Outcome:

  • Macroaggregated albumin (MAA) shunt fraction [ Time Frame: 12 Weeks ]
  • Exhaled nitric oxide (eNO) [ Time Frame: 12 Weeks ]


Original Secondary Outcome:

  • Macroaggregated albumin (MAA) shunt franction [ Time Frame: 12 Weeks ]
  • Exhaled nitric oxide (eNO) [ Time Frame: 12 Weeks ]


Information By: West China Hospital

Dates:
Date Received: May 21, 2014
Date Started: June 2014
Date Completion: September 2015
Last Updated: June 2, 2014
Last Verified: June 2014