Clinical Trial: Single Dose of 9-cis-retinoic Acid in Hepatic Patients

Study Status: Completed
Recruit Status: Completed
Study Type: Observational

Official Title: The Pharmacokinetics of a Single Dose of 9-cis-retinoic Acid (Alitretinoin, Toctino®) in Patients With Moderate to Severe Hepatic Insufficiency

Brief Summary: To test whether patients with hepatic insufficiency can tolerate one oral dose of 9-cis-retinoic acid and to test whether the metabolism of retinoic acid is altered.

Detailed Summary:
Sponsor: University Hospital, Gentofte, Copenhagen

Current Primary Outcome: A comparison of the metabolisation of retinoic acid in patients with hepatic insufficiency and controls [ Time Frame: 24 hours ]

Analysis on samples


Original Primary Outcome: Same as current

Current Secondary Outcome:

Original Secondary Outcome:

Information By: University Hospital, Gentofte, Copenhagen

Dates:
Date Received: June 21, 2013
Date Started: December 2010
Date Completion:
Last Updated: June 28, 2013
Last Verified: June 2013