Clinical Trial: Rifaximin in Minimal Hepatic Encephalopathy
Study Status: Completed
Recruit Status: Completed
Study Type: Interventional
Official Title: Effect of Rifaximin on Driving Performance, Psychometric Test Performance and Quality of Life in Cirrhotic Patients With Minimal Hepatic Encephalopathy: Randomized, Double
Brief Summary: The purpose of this study is to determine whether alteration of gut flora with rifaximin can lead to improvement in driving performance, psychometric test performance, and quality of life in patients with minimal hepatic encephalopathy (MHE) and cirrhosis in a randomized, blinded, placebo-controlled trial.
Detailed Summary:
Sponsor: Hunter Holmes Mcguire Veteran Affairs Medical Center
Current Primary Outcome: Driving performance [ Time Frame: 8 weeks ]
Original Primary Outcome: Same as current
Current Secondary Outcome:
- Psychometric test performance [ Time Frame: 8 weeks ]
- Quality of life [ Time Frame: 8 weeks ]
Original Secondary Outcome: Psychometric test performance, quality of life [ Time Frame: 8 weeks ]
Information By: Hunter Holmes Mcguire Veteran Affairs Medical Center
Dates:
Date Received: September 20, 2007
Date Started: October 2007
Date Completion:
Last Updated: March 19, 2013
Last Verified: March 2013
