Clinical Trial: Bone Status on Patients With Genetic Hemochromatosis: a 3 Years Descriptive and Evolutionary Study
Study Status: Completed
Recruit Status: Completed
Study Type: Observational
Official Title: Bone Status on Patients With Genetic Hemochromatosis : a 3 Years Descriptive and Evolutionary Study.
Brief Summary: The purpose of this study is to describe bone status on patients with genetic hemochromatosis, at diagnostic time and his evolution under treatment.
Detailed Summary: Bone diseases have been recognized recently as complications of genetic hemochromatosis. Further studies are needed to describe the role of iron in bone injuries. The purpose of this study is to describe bone status on patients with genetical hemochromatosis, at diagnostic time and his evolution under treatment.
Sponsor: Rennes University Hospital
Current Primary Outcome: Bone mineral density [ Time Frame: Change from baseline in bone mineral density at three years ]
Original Primary Outcome: Same as current
Current Secondary Outcome:
- Predictive value of iron overload on Bone Mineral Density [ Time Frame: 1 day ]
- Number of vertebral fractures [ Time Frame: 3 years ]
- Number of peripheral fractures [ Time Frame: 3 years ]
- Number and location of joint lesions detected by the examination (pain and swelling) [ Time Frame: 3 years ]
- Determination of genetic polymorphism of BMP 2 and 4 [ Time Frame: Baseline ]
Original Secondary Outcome: Same as current
Information By: Rennes University Hospital
Dates:
Date Received: March 1, 2012
Date Started: July 2008
Date Completion:
Last Updated: May 26, 2015
Last Verified: May 2015