Clinical Trial: Aspirin and the Risk of Microscopic Hematuria in Asymptomatic Screened Population

Study Status: Completed
Recruit Status: Completed
Study Type: Observational

Official Title:

Brief Summary: Aspirin can increase the risk of bleeding tendency. However, correlation between aspirin treatment and hematuria in general population is not well known. The investigators will evaluate whether daily use of aspirin increase the risk of microscopic hematuria in healthy large screened populations.

Detailed Summary:
Sponsor: Seoul National University Hospital

Current Primary Outcome: Incidence rate of the microscopic hematuria [ Time Frame: at the screening ]

>4 RBC/HPF in urine microscopy


Original Primary Outcome: Same as current

Current Secondary Outcome:

  • Detection rate of significant cause for microscopic hematuria [ Time Frame: whitin 12 months after screening ]
    • Among participants who had microscopic hematuria at the screening
    • By imaging study or cystoscopy
    • At the screening or within 12 months after screening

    • Significant cause for microscopic hematuria

      1. urinary stone
      2. renal mass (benign or malignant / not simple cyst)
      3. urothelial cancer
      4. other lesions (clinically relevant lesions determined by researchers)
  • Incidence rate of persistent microscopic hematuria [ Time Frame: within 12 months ]
    • Among participants who had microscopic hematuria at the screening
    • Determined by repeated urine microscopy


Original Secondary Outcome:

  • Detection rate of significant cause for microscopic hematuria [ Time Frame: whitin 12 months after screening ]
    • Among participants who had microscopic hematuria at the screening
    • By imaging study or cystoscopy
    • At the screening or within 12 months after screening

    • Significant casue for microscopic hemautira

      1. urinary stone
      2. renal mass (benign or malignant / not simple cyst)
      3. urothelial cancer
      4. other lesions (clinically relevant lesions determined by researchers)
  • Incidence rate of persistent microscopic hematuria [ Time Frame: within 12 months ]
    • Among participants who had microscopic hematuria at the screening
    • Determined by repeated urine microscopy


Information By: Seoul National University Hospital

Dates:
Date Received: June 6, 2012
Date Started: August 2012
Date Completion:
Last Updated: August 27, 2012
Last Verified: August 2012