Clinical Trial: The Safety & Efficacy of Terlipressin vs Octreotide for the Control of Variceal Bleed

Study Status: Completed
Recruit Status: Completed
Study Type: Interventional

Official Title: Efficacy And Safety Of Terlipressin Vs Octreotide As Adjuvant Therapy In Bleeding Esophageal Varices

Brief Summary: Terlipressin and Octreotide are two common agents used as adjuvants in the management of variceal bleeding. Both agents have been claimed equivalent to endoscopic therapy in randomized studies. There are no head to head clinical trials of these two agents available in the literature. We aimed to compare the efficacy and safety of Terlipressin and Octreotide in combination with Endoscopic Variceal band Ligation (EVL)in patients presenting with Esophageal Variceal Bleed (EVB).

Detailed Summary:

The effectiveness of combining Endoscopic treatment with Octreotide or Terlipressin has not been prospectively studied in esophageal variceal hemorrhage (EVH).

This prospective, randomized clinical trial will help us in better patient management more efficiently and cost effectively.

Sponsor: Aga Khan University

Current Primary Outcome: Safety & Efficacy [ Time Frame: 5 days ]

Original Primary Outcome: Same as current

Current Secondary Outcome:

Original Secondary Outcome:

Information By: Aga Khan University

Dates:
Date Received: September 24, 2007
Date Started: May 2004
Date Completion:
Last Updated: December 4, 2007
Last Verified: September 2007