Clinical Trial: Plantar Faciitis and Diabetes Mellitus

Study Status: Completed
Recruit Status: Completed
Study Type: Observational

Official Title: Increased Calcaneal Spur Incidence in Patients With Obesity and Type 2 Diabetes Mellitus

Brief Summary: Obesity is a risk factor for calcaneal spur (CS) formation which is supposed to originate from chronic plantar fasciitis. Diabetes mellitus may contribute to the risk of CS by decreased ability of tissue repair and increased reactive ossification. Thus, the investigators aimed to determine CS incidence in asymptomatic obese subjects with and without type 2 diabetes mellitus (T2DM).

Detailed Summary:

OBJECTIVE-Obesity is a risk factor for calcaneal spur (CS) formation which is supposed to originate from chronic plantar fasciitis. Diabetes mellitus may contribute to the risk of CS by decreased ability of tissue repair and increased reactive ossification. Thus, the investigators aimed to determine CS incidence in asymptomatic obese subjects with and without type 2 diabetes mellitus (T2DM).

RESEARCH DESIGN AND METHODS—Ninety-three obese patients with T2DM and forty-two obese subjects without any metabolic disturbances as control were evaluated with lateral calcaneal x-ray in blinded fashion by a radiologist. All participants were informed and written consents have been obtained. Control cases were subjected to 75g glucose challenge test and glucose intolerant subjects were excluded.

RESULTS—T2DM and control groups were statistically similar in mean age (59±10.5 vs. 55±8 yrs, P=0.196, respectively) and mean body mass index (BMI)(35.1±4.3 vs. 33.1±3.3 kg/m2, P=0.073, respectively). Existence of calcaneal spur was 72% in 93 patients (77%) in T2DM group and 24 in 42 (57%) in control group. Groups were significantly different according to existence of CS (P=0.023). Mean age and mean BMI were significantly higher in diabetic patients with calcaneal spur than diabetic patients without calcaneal spur (p=0.001 and p=0.015, respectively). There was positive correlation between existence of calcaneal spur and peripheral neuropathy (p=0,043) in diabetics but no significant relation between existence of CS and glycolysed hemoglobin levels or diabetes duration (all P>0.05).

CONCLUSIONS—Clinicians should pay attention the increased incidence of CS in patients with T2DM to avoid foot complications.

Sponsor: Gulhane School of Medicine

Current Primary Outcome: Increased Calcaneal Spur Incidence in Patients With Obesity and Type 2 Diabetes Mellitus [ Time Frame: 3 months ]

Original Primary Outcome: Increased Calcaneal Spur Incidence in Patients With Obesity and Type 2 Diabetes Mellitus [ Time Frame: 7 months ]

Current Secondary Outcome:

Original Secondary Outcome:

Information By: Gulhane School of Medicine

Dates:
Date Received: December 13, 2010
Date Started: February 2009
Date Completion:
Last Updated: June 17, 2011
Last Verified: October 2008