Clinical Trial: Fluid Balance During Closure of Atrial Septal Defect

Study Status: Completed
Recruit Status: Completed
Study Type: Observational

Official Title: Protein Distribution and Colloid Osmotic Pressure in Children With Volume and Pressure Loading Due to Congenital Heart Defects

Brief Summary: This project will evaluate fluid balance and oedema formation in children with the same congenital heart disease (Atrial Septal Defect) who will either go through heart surgery with the use of Cardio Pulmonary Bypass and hypothermia or through interventional catheterization. The investigators will measure interstitial colloid osmotic pressure, distribution of proteins and cytokines. The study hypothesis is that "Oedema developed during heart surgery is caused by reduced colloid osmotic pressure gradient through the capillary membrane".

Detailed Summary:
Sponsor: Oslo University Hospital

Current Primary Outcome: Interstitial colloid osmotic pressure [ Time Frame: During surgery or interventional closure ]

Original Primary Outcome: Same as current

Current Secondary Outcome:

Original Secondary Outcome:

Information By: Oslo University Hospital

Dates:
Date Received: December 21, 2012
Date Started: February 2013
Date Completion:
Last Updated: April 8, 2017
Last Verified: April 2017