Clinical Trial: To Evaluate if Wide Blood Sugar Fluctuations Lead to Injury of Heart Function and Heart Nerves
Study Status: Active, not recruiting
Recruit Status: Active, not recruiting
Study Type: Observational
Official Title: Cardiac Autonomic Neuropathy and Myocardial Dysfunction in Type 1 Diabetes
Brief Summary: This proposal will test if, in patients with type 1 diabetes, wide blood glucose fluctuations lead to the injury to heart nerves , called cardiac autonomic neuropathy (CAN), and to impaired heart contractile (pumping) function and heart failure. It will also evaluate the natural history of heart failure and enhanced cardiac risk in patients with type 1 diabetes in the current standard of diabetes care.
Detailed Summary:
Sponsor: University of Michigan
Current Primary Outcome: Heart rate (HR) Variability Studies [ Time Frame: Three years ]
Original Primary Outcome: Same as current
Current Secondary Outcome: Positron Emission Tomography (PET) scan [ Time Frame: Test to be completed at baseline and end of study (3yrs) ]
Original Secondary Outcome: Same as current
Information By: University of Michigan
Dates:
Date Received: July 26, 2010
Date Started: May 2010
Date Completion: August 2017
Last Updated: October 24, 2016
Last Verified: October 2016