Clinical Trial: Cardiac Uptake of Metformin, Visualized by Positron Emission Tomography

Study Status: Recruiting
Recruit Status: Recruiting
Study Type: Interventional

Official Title: Cardiac Uptake of Metformin and Expression of Metformin Membrane Transporter Proteins in the Human Failing Myocardium

Brief Summary:

The purpose of the study is to evaluate if metformin is taken up into the failing myocardium. Recent experimental and epidemiological studies have shown beneficial effects of metformin on heart failure. It is unknown whether this effect is direct or indirect.

The aim of the study is to investigate if metformin is taken up in heart failure using a novel 11C-metformin tracer and positron emission tomography (PET).


Detailed Summary:
Sponsor: Henrik Wiggers

Current Primary Outcome: Metformin uptake in the failing myocardium [ Time Frame: 12 months ]

Cardiac uptake is evaluated through analysis of acquired PET-images.


Original Primary Outcome: Same as current

Current Secondary Outcome:

Original Secondary Outcome:

Information By: Aarhus University Hospital

Dates:
Date Received: April 18, 2017
Date Started: April 20, 2017
Date Completion: May 31, 2018
Last Updated: April 18, 2017
Last Verified: April 2017