Clinical Trial: Intracranial Pressure During Migraine

Study Status: Recruiting
Recruit Status: Recruiting
Study Type: Observational

Official Title: Measure of Intracranial Pressure Variations During Migraine Attacks

Brief Summary: An increase in intracranial pressure (ICP) during migraine attacks is possible and could contribute to pain initiation and maintenance. From now on, it was not possible to measure ICP in a non-invasive way. The development of a new tool allows non-invasive self-measures of ICP variations. Thus, it is possible for the first time to look for such ICP variations during migraine attacks and to conclude if this mechanism is implied in the pathophysiology of migraine.

Detailed Summary: Womens presenting with regular menstrual migraine treated with triptans will be included in the study. Self-measure of ICP will be performed outside and during menstrual migraine attacks. The potential variations will be compared to the measures done on matched healthy women outside and during menses.
Sponsor: University Hospital, Clermont-Ferrand

Current Primary Outcome: Intracranial pressure variations [ Time Frame: during menstrual migraine attacks ]

Measured during menstrual migraine attacks compared to ICP in non-migraine days and in matched healthy women


Original Primary Outcome: Same as current

Current Secondary Outcome:

  • Relationships between ICP variations and clinical parameters [ Time Frame: during menstrual migraine attacks ]
    Age, BMI, pain intensity, pulsating pain, allodynia, nausea, photophobia, phonophobia, dizziness, tinnitus
  • Relationships between ICP variations and pain relief [ Time Frame: during menstrual migraine attacks ]


Original Secondary Outcome: Same as current

Information By: University Hospital, Clermont-Ferrand

Dates:
Date Received: May 11, 2017
Date Started: July 21, 2014
Date Completion: July 2018
Last Updated: May 11, 2017
Last Verified: May 2017